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產(chǎn)品中心抗體Polyclonal AntibodyK106572PAnti-GAD65 Polyclonal Antibody
產(chǎn)品型號：K106572P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
訪 問 量 ：1001
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Anti-GAD65 Polyclonal Antibody
| 英文名稱 | Anti-GAD65 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | GAD2;DCE2;MGC161605;MGC161607 |
| 應(yīng)用 | WB IHC |
| 稀釋比例 | WB 1:2000-5000.IHC 1:50-200. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 65kDa |
| Gene ID | 2572 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human GAD65 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human GAD65 |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | Q05329 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. |
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