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產(chǎn)品中心抗體Polyclonal AntibodyK106519PAnti-NQO1 Polyclonal Antibody
產(chǎn)品型號：K106519P
更新時間：2022-08-15
廠商性質(zhì)：生產(chǎn)廠家
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產(chǎn)品分類
Anti-NQO1 Polyclonal Antibody
| 英文名稱 | Anti-NQO1 Polyclonal Antibody |
|---|---|
| 宿主 | Rabbit |
| 別名 | DHQU;DIA4;DTD;NMOR1;NMORI;QR1 |
| 應(yīng)用 | WB |
| 稀釋比例 | WB 1:3000. |
| 交叉反應(yīng) | Human Mouse Rat |
| 蛋白分子量 | 27kDa |
| Gene ID | 1728 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 儲存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 純化方法 | Affinity purification |
| 亞型 | IgG |
| 免疫原 | A synthetic peptide of human NQO1 |
| 性狀 | 液體 |
| Public Immunogen Range | A synthetic peptide of human NQO1 |
| Subcellular Locations | Cytoplasm Cell membrane |
| Swiss Prot | P15559 |
| 克隆類型 | Polyclonal Antibody |
| 背景資料 | This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
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