Anti-CD130 Polyclonal Antibody
應(yīng)用 WB
稀釋比例WB 1:3000.
交叉反應(yīng)Human Mouse Rat

產(chǎn)品型號(hào)：K106480P

更新時(shí)間：2022-08-15

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Anti-CD130 Polyclonal Antibody

英文名稱	Anti-CD130 Polyclonal Antibody
宿主	Rabbit
別名	CDW130;GP130;IL-6RB;IL6ST;IL-6R beta
應(yīng)用	WB
稀釋比例	WB 1:3000.
交叉反應(yīng)	Human Mouse Rat
蛋白分子量	65/125kDa
Gene ID	3572
保存	Store at -20°C. Avoid freeze / thaw cycles.
儲(chǔ)存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
純化方法	Affinity purification
亞型	IgG
免疫原	A synthetic peptide of human CD130
性狀	液體
Public Immunogen Range	A synthetic peptide of human CD130
Subcellular Locations	Cell membrane Nucleus Extracellular matrix
Swiss Prot	P40189
克隆類型	Polyclonal Antibody
背景資料	The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17.